Ensemble refinement model

PDB 7B4N|dpdb_jm6e0w4y

Ensemble refinement model

Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human wild-type p53DBD bound to DNA and MQ: wt-DNA-MQ (II)

Program
PHENIX 2.0_5824
Model type
Ensemble
Purpose
Refinement
Atoms
192,036
Residues
204
Protein chains
2
Alternate-location fraction
0%
Ligands
FMT, QN8, QNN, ZN

Evaluations

R-work
0.180
R-free
0.208
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Cellular tumor antigen p53200
  • Constructp53 human DNA binding domain
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
DNA target12—
  • Constructp53 DNA target
  • Mutations'

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations