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Deposited model

PDB 2H54|dpdb_jrct8xp5

Deposited model

Crystal structure of human caspase-1 (Thr388->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)

Program
REFMAC 5.2.0005
Model type
Deposited
Purpose
Reference
Authors
Scheer, J.M., Wells, J.A., Romanowski, M.J.
Atoms
2,359
Residues
263
Protein chains
3
Unmodeled fraction
2.95%

Evaluations

R-work
0.215
R-free
0.246
Clashscore
3.9

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Caspase-1178
  • Constructp20 subunit, residues 120-297
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Caspase-188
  • Constructp10 subunit, residues 317-404
  • MutationT388A
Entity 3
MoleculeChainsLengthOrganismUniProtDetails
N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide5———

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations