Deposited model

PDB 3K54|dpdb_jvfbdofb

Deposited model

Structures of human Bruton's tyrosine kinase in active and inactive conformations suggests a mechanism of activation for TEC family kinases.

Program
REFMAC 5.5.0088
Model type
Deposited
Purpose
Reference
Authors
Marcotte, D.J., Liu, Y.-T., Arduini, R.M., Hession, C.A., Miatkowski, K., Wildes, C.P., Cullen, P.F., Hopkins, B.T., Mertsching, E., Jenkins, T.J., Romanowski, M.J., Baker, D.P., Silvian, L.F.
Atoms
2,212
Residues
243
Protein chains
1
Unmodeled fraction
14.13%

Evaluations

R-work
0.199
R-free
0.258
Clashscore
13.5

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase BTK283
  • ConstructBTK kinase domain, residues 382-659
  • MutationY551E

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations