Ensemble refinement model

PDB 5NX1|dpdb_k5bxljxl

Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human Kallikrein 6 for Cancer Therapy

Evaluations

R-work

0.180

R-free

0.223

Clashscore

—

The same in every model of this entry.

Entity 1
Molecule	Chains	Length	Organism	UniProt	Details
Kallikrein-6		223	Homo sapiens9606	Q92876SIFTS · 2026_03	—

Entity 2
Molecule	Chains	Length	Organism	UniProt	Details
Amyloid-beta A4 protein		25	Homo sapiens9606	P05067SIFTS · 2026_03	ConstructUNP residues 289-301

Entity 3
Molecule	Chains	Length	Organism	UniProt	Details
Amyloid-beta A4 protein		56	Homo sapiens9606	P05067SIFTS · 2026_03	ConstructUNP residues 302-346

Entity 4
Molecule	Chains	Length	Organism	UniProt	Details
Amyloid-beta A4 protein		81	Homo sapiens9606	P05067SIFTS · 2026_03	ConstructUNP residues 289-346

L0 Raw

L1 Processed

L2 Models

L3 Evaluations