Deposited model

PDB 2F4J|dpdb_khxnm4ux

Deposited model

Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680

Program
CNS 1.1
Model type
Deposited
Purpose
Reference
Authors
Young, M.A., Shah, N.P., Chao, L.H., Zarrinkar, P., Sawyers, P., Kuriyan, J.
Atoms
2,572
Residues
287
Protein chains
1
Unmodeled fraction
0%

Evaluations

R-work
0.207
R-free
0.239
Clashscore
10.5

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Proto-oncogene tyrosine-protein kinase ABL1287
  • ConstructKinase domain, residues 227-513
  • MutationH396P

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations