Rerefined model

PDB 2FVJ|dpdb_l6o5hp3q

Rerefined model

A novel anti-adipogenic partial agonist of peroxisome proliferator-activated receptor-gamma (PPARG) recruits pparg-coactivator-1 alpha (PGC1A) but potentiates insulin signaling in vitro

Program: PHENIX 2.0_5824
Model type: Multiconformer
Purpose: Refinement
Atoms: 2,435

Residues: 268
Protein chains: 2
Alternate-location fraction: 0%
Ligands: GOL, RO0

Evaluations

R-work

0.203

R-free

0.265

Clashscore

7.6

Macromolecules

The same in every model of this entry.

Entity 1
Molecule	Chains	Length	Organism	UniProt	Details
Peroxisome proliferator-activated receptor gamma		271	Homo sapiens9606	P37231SIFTS · 2026_03	ConstructLIGAND BINDING DOMAIN, RESIDUES 207-477

Entity 2
Molecule	Chains	Length	Organism	UniProt	Details
Nuclear receptor coactivator 1		13	Homo sapiens9606	Q15788SIFTS · 2026_03	ConstructCOACTIVATOR FRAGMENT SRC-1, 13-mer peptide from Nuclear receptor coactivator 1

Data

L0 Raw

L1 Processed

L2 Models

L3 Evaluations