Deposited model

PDB 3K5K|dpdb_m8zkgvbt

Deposited model

Discovery of a 2,4-Diamino-7-aminoalkoxy-quinazoline as a Potent Inhibitor of Histone Lysine Methyltransferase, G9a

Program
REFMAC 5.5.0102
Model type
Deposited
Purpose
Reference
Authors
Dong, A., Wasney, G.A., Liu, F., Chen, X., Allali-Hassani, A., Senisterra, G., Chau, I., Bountra, C., Weigelt, J., Edwards, A.M., Arrowsmith, C.H., Frye, S.V., Bochkarev, A., Brown, P.J., Jin, J., Vedadi, M., Structural Genomics Consortium (SGC)
Atoms
4,816
Residues
541
Protein chains
2
Unmodeled fraction
4.42%
Ligand
ZN

Evaluations

R-work
0.209
R-free
0.264
Clashscore
1.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Histone-lysine N-methyltransferase, H3 lysine-9 specific 3283
  • ConstructUNP residues 913-1193, SET domain

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations