Dynamic PDB
Log in

Rerefined model

PDB 2HBZ|dpdb_mmnga2wh

Rerefined model

Crystal structure of human caspase-1 (Arg286->Ala, Glu390->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)

Program
PHENIX 2.0_5824
Model type
Multiconformer
Purpose
Refinement
Atoms
2,331
Residues
253
Protein chains
3
Alternate-location fraction
2.37%
Ligands
CF0, PHQ

Evaluations

R-work
0.217
R-free
0.268
Clashscore
13.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Caspase-1178
  • ConstructP20 Subunit, Residues 120-297
  • MutationR286A
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Caspase-188
  • ConstructP10 Subunit, Residues 317-404
  • MutationE390A
Entity 3
MoleculeChainsLengthOrganismUniProtDetails
PHQ-VAD-fluoromethylketone inhibitor5———

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations