Deposited model

PDB 4DSU|dpdb_mtooz4ku

Deposited model

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Program
PHENIX 1.6.4_486)
Model type
Deposited
Purpose
Reference
Authors
Oh, A., Maurer, T., Garrenton, L.S., Pitts, K., Anderson, D.J., Skelton, N.J., Fauber, B.P., Pan, B., Malek, S., Stokoe, D., Ludlam, M., Bowman, K.K., Wu, J., Giannetti, A.M., Starovasnik, M.A., Mellman, I., Jackson, P.K., Ruldolph, J., Fang, G., Wang, W.
Atoms
1,488
Residues
177
Protein chains
1
Unmodeled fraction
6.35%
Ligands
GDP, MG

Evaluations

R-work
0.160
R-free
0.203
Clashscore
6.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
GTPase KRas, isoform 2B189
  • MutationG12D

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations