Deposited model

PDB 5KCE|dpdb_nkh7y2pa

Deposited model

Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with an N-methyl, 2-chlorobenzyl OBHS-N derivative

Program
PHENIX 1.9_1690
Model type
Deposited
Purpose
Reference
Authors
Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Dharmarajan, V., Goswami, D., Kastrati, I., Novick, S., Nowak, J., Zhou, H.B., Boonmuen, N., Zhao, Y., Min, J., Frasor, J., Katzenellenbogen, B.S., Griffin, P.R., Katzenellenbogen, J.A., Nettles, K.W.
Atoms
4,023
Residues
480
Protein chains
4
Unmodeled fraction
11.11%

Evaluations

R-work
0.192
R-free
0.250
Clashscore
4.6

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Estrogen receptor257
  • Constructligand-binding domain, UNP residues 125-381
  • MutationY537S
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Nuclear receptor coactivator 213
  • ConstructNuclear receptor-interacting peptide, UNP residues 686-698

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations