Ensemble refinement model

PDB 4QQ5|dpdb_p1osoxbn

Ensemble refinement model

Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex With FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations

Program
PHENIX phenix.ensemble_refinement
Model type
Ensemble
Purpose
Refinement
Atoms
115,023
Residues
275
Protein chains
1
Alternate-location fraction
0%
Ligand
37O

Evaluations

R-work
0.155
R-free
0.198
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Fibroblast growth factor receptor 4323
  • ConstructKinase domain of FGF Receptor 4
  • MutationsR669E V550L

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations