Deposited model

PDB 5TQ4|dpdb_p3kr1c5t

Deposited model

Design and Synthesis of a pan-JAK Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin

Program
REFMAC 5.8.0073
Model type
Deposited
Purpose
Reference
Authors
Chrencik, J., Jones, P.
Atoms
2,530
Residues
292
Protein chains
1
Unmodeled fraction
2.01%

Evaluations

R-work
0.247
R-free
0.279
Clashscore
0.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase JAK2298
  • ConstructUNP residues 837-1132
  • MutationsM1073S F1076T

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations