Deposited model

PDB 4AGW|dpdb_pjlvivri

Deposited model

Discovery of a small molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases

Program
PHENIX (PHENIX.REFINE)
Model type
Deposited
Purpose
Reference
Authors
Weisberg, E., Choi, H.G., Seeliger, M., Gray, N., Griffin, J.D.
Atoms
4,419
Residues
515
Protein chains
2
Unmodeled fraction
9.97%

Evaluations

R-work
0.226
R-free
0.271
Clashscore
47.4

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC286
  • ConstructKINASE DOMAIN, RESIDUES 251-533

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations