Ensemble refinement model

PDB 7K1H|dpdb_q7rqz924

Ensemble refinement model

EGFR L858R/V948R in complex with osimertinib and allosteric inhibitor JBJ-09-063

Program
PHENIX phenix.ensemble_refinement
Model type
Ensemble
Purpose
Refinement
Atoms
425,065
Residues
1,743
Protein chains
6
Alternate-location fraction
0%
Ligands
VNS, YY3

Evaluations

R-work
0.188
R-free
0.268
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Epidermal growth factor receptor331
  • Constructkinase domain
  • MutationsL858R V948R

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations