Deposited model

PDB 6QGK|dpdb_qtdhu8sx

Deposited model

Structure of human Bcl-2 in complex with THIQ-phenyl pyrazole compound

Program
REFMAC 5.8.0230
Model type
Deposited
Purpose
Reference
Authors
Dokurno, P., Murray, J., Davidson, J., Chen, I., Davis, B., Graham, C.J., Harris, R., Jordan, A.M., Matassova, N., Pedder, C., Ray, S., Roughley, S., Smith, J., Walmsley, C., Wang, Y., Whitehead, N., Williamson, D.S., Casara, P., Le Diguarher, T., Hickman, J., Stark, J., Kotschy, A., Geneste, O., Hubbard, R.E.
Atoms
1,365
Residues
148
Protein chains
1
Unmodeled fraction
16.38%

Evaluations

R-work
0.166
R-free
0.202
Clashscore
8.3

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Bcl-2-like protein 1177
  • MutationsH20S E42A E44A L95Q R106L E114Q F124G R127Y G128A R129S E135A E165A P168V L175A T178A E179T R183D

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations