Deposited model

PDB 3UW9|dpdb_qx0erm3e

Deposited model

Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K8acK12ac)

Program
REFMAC
Model type
Deposited
Purpose
Reference
Authors
Filippakopoulos, P., Felletar, I., Picaud, S., Keates, T., Muniz, J., Gileadi, O., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
Atoms
3,939
Residues
465
Protein chains
6
Unmodeled fraction
12.26%

Evaluations

R-work
0.200
R-free
0.257
Clashscore
3.3

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Bromodomain-containing protein 4127
  • Constructunp resideus 44-168
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
histone 4 peptide (H4K8acK12ac)11
  • Constructunp residues 8-18

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations