Deposited model

PDB 8A2D|dpdb_r9uo4s51

Deposited model

EGFR kinase domain (L858R/V948R) in complex with 2-[4-(difluoromethyl)-6-[2-[4-[[4-(hydroxymethyl)-1-piperidyl]methyl]phenyl]ethynyl]-7-methyl-indazol-2-yl]-2-spiro[6,7-dihydropyrrolo[1,2-c]imidazole-5,1'-cyclopropane]-1-yl-N-thiazol-2-yl-acetamide

Program
REFMAC 5.8.0267
Model type
Deposited
Purpose
Reference
Authors
Kuglstatter, A., Ehler, A.
Atoms
2,770
Residues
281
Protein chains
1
Unmodeled fraction
13.8%

Evaluations

R-work
0.163
R-free
0.179
Clashscore
7.3

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Epidermal growth factor receptor326
  • MutationsL858R V948R

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations