Deposited model

PDB 6XVA|dpdb_rjl3qvws

Deposited model

Crystal structure of the kinase domain of human c-KIT in complex with a type-II inhibitor bearing an acrylamide

Program
_software.os _software.pdbx_ordinal
Model type
Deposited
Purpose
Reference
Authors
Schimpl, M., McAuley, K., Hoyt, E.A., Thomas, M., Bodnarchuk, M.S., Lewis, H.J., Barratt, D., Deery, M.J., Ogg, D.J., Bernardes, G.J.L., Ward, R.A., Kettle, J.G., Waring, M.J.
Atoms
4,751
Residues
582
Protein chains
2
Unmodeled fraction
11.28%

Evaluations

R-work
0.196
R-free
0.245
Clashscore
1.7

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Mast/stem cell growth factor receptor Kit,Mast/stem cell growth factor receptor Kit328
  • Constructprotein kinase domain (551-934 del[688-755]),protein kinase domain (551-934 del[688-755])
  • MutationsI563S V569S Y609Q L631S M651E I662H D768H R804N V825D C844S L890S H894Y L912D L923D

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations