Deposited model

PDB 5UGA|dpdb_t17pe7h7

Deposited model

Crystal structure of the EGFR kinase domain (L858R, T790M, V948R) in complex with 4-(4-{[2-{[(3S)-1-acetylpyrrolidin-3-yl]amino}-9-(propan-2-yl)-9H-purin-6-yl]amino}phenyl)-1-methylpiperazin-1-ium

Program
CNX 2005
Model type
Deposited
Purpose
Reference
Authors
Gajiwala, K.S., Ferre, R.A.
Atoms
2,530
Residues
283
Protein chains
1
Unmodeled fraction
13.98%

Evaluations

R-work
0.233
R-free
0.264
Clashscore
5.5

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Epidermal growth factor receptor329
  • ConstructUNP residues 695-1022
  • MutationsL858R T790M V948R

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations