Deposited model

PDB 2C6E|dpdb_td55y44k

Deposited model

Aurora A kinase activated mutant (T287D) in complex with a 5- aminopyrimidinyl quinazoline inhibitor

Program
CNX 2000
Model type
Deposited
Purpose
Reference
Authors
Pauptit, R.A., Pannifer, A.D., Breed, J., McMiken, H.H.J., Rowsell, S., Anderson, M.
Atoms
4,197
Residues
497
Protein chains
2
Unmodeled fraction
12.19%

Evaluations

R-work
0.200
R-free
0.270
Clashscore
12.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
SERINE/THREONINE-PROTEIN KINASE 6283
  • ConstructCATALYTIC KINASE DOMAIN, RESIDUES 123-401
  • MutationsYES

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations