Deposited model

PDB 3IOK|dpdb_toq80u6l

Deposited model

2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2

Program
REFMAC
Model type
Deposited
Purpose
Reference
Authors
Zuccola, H.J., Ledeboer, M.W., Pierce, A.C.
Atoms
2,511
Residues
287
Protein chains
1
Unmodeled fraction
8.31%

Evaluations

R-work
0.224
R-free
0.270
Clashscore
4.7

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase JAK2313
  • Constructjak2 kinase domain (UNP residues 842-1132)

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations