Deposited model

PDB 5TQ6|dpdb_ujeunwh5

Deposited model

Design and Synthesis of a pan-JAK Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin

Program
REFMAC 5.8.0073
Model type
Deposited
Purpose
Reference
Authors
Chrencik, J., Jones, P.
Atoms
4,846
Residues
549
Protein chains
2
Unmodeled fraction
9.7%

Evaluations

R-work
0.257
R-free
0.289
Clashscore
10.7

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase JAK2304
  • ConstructUNP residues 837-1132
  • MutationsM1073S F1076T

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations