Ensemble refinement model

PDB 6FIQ|dpdb_va1na7qd

Ensemble refinement model

DDR1, 1-(1H-indazole-5-carbonyl)-5'-methoxy-1'-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]spiro[piperidine-4,3'-pyrrolo[3,2-b]pyridine]-2'-one, 1.790A, P212121, Rfree=23.8%

Program: PHENIX phenix.ensemble_refinement
Model type: Ensemble
Purpose: Refinement
Atoms: 124,525

Residues: 293
Protein chains: 1
Alternate-location fraction: 0%
Ligands: CL, DJW

Evaluations

R-work

0.184

R-free

0.215

Clashscore

—

Macromolecules

The same in every model of this entry.

Entity 1
Molecule	Chains	Length	Organism	UniProt	Details
Epithelial discoidin domain-containing receptor 1		321	Homo sapiens9606	Q08345SIFTS · 2026_03	Constructtyrosine kinase domain, residues 593-913 MutationsDEL(730-735)

Data

L0 Raw

L1 Processed

L2 Models

L3 Evaluations