Rerefined model

PDB 4CLJ|dpdb_vbxpi4vg

Rerefined model

Structure of L1196M Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).

Program
PHENIX 2.0_5824
Model type
Multiconformer
Purpose
Refinement
Atoms
2,658
Residues
296
Protein chains
1
Alternate-location fraction
0%
Ligand
5P8

Evaluations

R-work
0.172
R-free
0.212
Clashscore
4.3

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
ALK TYROSINE KINASE RECEPTOR327
  • ConstructTYROSINE KINASE DOMAIN, RESIDUES 1093-1411
  • MutationsYES

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations