Deposited model

PDB 4I12|dpdb_w72jptdv

Deposited model

Design and synthesis of thiophene dihydroisoquinolins as novel BACE-1 inhibitors

Program
REFMAC
Model type
Deposited
Purpose
Reference
Authors
Lougheed, J.C., Brecht, E., Yao, N.H.
Atoms
3,157
Residues
374
Protein chains
1
Unmodeled fraction
7.88%
Ligand
ZN

Evaluations

R-work
0.228
R-free
0.283
Clashscore
8.7

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Beta-secretase 1406
  • Constructunp residues 57-453

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations