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Ensemble refinement model

PDB 7NUS|dpdb_weq353xk

Ensemble refinement model

X-RAY STRUCTURE OF HDM2/CMR19 AT 1.45A: Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitors

Program
PHENIX 1.21.2_5419
Model type
Ensemble
Purpose
Refinement
Atoms
289,058
Residues
299
Protein chains
6
Alternate-location fraction
0%
Ligands
5JP, BIF, CCS, CL, GM1, SO4

Evaluations

R-work
0.145
R-free
0.176
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
E3 ubiquitin-protein ligase Mdm296
  • ConstructN-terminal domain, p53 binding domain
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
p53/MDM2 macrocyclic peptide inhibitor15——

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations