Deposited model

PDB 6UT0|dpdb_wt2gjozm

Deposited model

Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of Cancer

Program
REFMAC 5.8.0253
Model type
Deposited
Purpose
Reference
Authors
Vigers, G.P., Smith, D.J.
Atoms
6,157
Residues
677
Protein chains
4
Unmodeled fraction
0.44%
Ligands
GDP, M1X, MG

Evaluations

R-work
0.175
R-free
0.222
Clashscore
4.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
GTPase KRas170
  • MutationsG12C C51S C80L C118S

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations