Ensemble refinement model

PDB 4R6V|dpdb_wy5m501l

Ensemble refinement model

Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex with FIIN-3, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR kinase Gate-Keeper Mutations

Program
PHENIX phenix.ensemble_refinement
Model type
Ensemble
Purpose
Refinement
Atoms
91,001
Residues
273
Protein chains
1
Alternate-location fraction
0%
Ligands
FI3, SO4

Evaluations

R-work
0.155
R-free
0.211
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Fibroblast growth factor receptor 4323
  • ConstructTyrosine Kinase Domain of FGF receptor 4
  • MutationsR664E V550L

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations