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Deposited model

PDB 3OXI|dpdb_x2s9esoq

Deposited model

Design and Synthesis of Disubstituted Thiophene and Thiazole Based Inhibitors of JNK for the Treatment of Neurodegenerative Diseases

Program
REFMAC 5.2.0019
Model type
Deposited
Purpose
Reference
Authors
Hom, R.K., Bowers, S., Sealy, J., Truong, A., Probst, G.D., Neitzel, M., Neitz, J., Fang, L., Brogley, L., Wu, J., Konradi, A.W., Sham, H., Toth, G., Pan, H., Yao, N., Artis, D.R.
Atoms
2,809
Residues
332
Protein chains
2
Unmodeled fraction
10.75%

Evaluations

R-work
0.229
R-free
0.275
Clashscore
15.1

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Mitogen-activated protein kinase 10362
  • ConstructUNP residues 40 to 401
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Mitogen-activated protein kinase 8 interacting protein 110
  • ConstructUNP residues 158 to 167

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations