Deposited model

PDB 3RCJ|dpdb_x7aay11s

Deposited model

Rapid preparation of triazolyl substituted NH-heterocyclic kinase inhibitors via one-pot Sonogashira coupling TMS-deprotection CuAAC sequence

Program
CNX 2005
Model type
Deposited
Purpose
Reference
Authors
Graedler, U., Dorsch, D., Merkul, E., Klukas, F., Sirrenberg, C., Greiner, H.E., Mueller, T.J.J.
Atoms
2,463
Residues
282
Protein chains
1
Unmodeled fraction
9.32%

Evaluations

R-work
0.217
R-free
0.198
Clashscore
7.3

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
3-phosphoinositide-dependent protein kinase 1311
  • ConstructProtein kinase domain, residues 50-359
  • MutationsG240Y A244Q

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations