Deposited model

PDB 6UF0|dpdb_xnvzf1p8

Deposited model

Crystal structure of N-(4-((4-methoxy-N-(2,2,2-trifluoroethyl)phenyl)sulfonamido)isoquinolin-1-yl)-N-((4-methoxyphenyl)sulfonyl)glycine bound to human Keap1 Kelch domain

Program
REFMAC
Model type
Deposited
Purpose
Reference
Authors
Lazzara, P.R., David, B.P., Ankireddy, A., Richardson, B.G., Dye, K., Ratia, K.M., Reddy, S.P., Moore, T.W.
Atoms
4,788
Residues
570
Protein chains
2
Unmodeled fraction
1.72%
Ligand
NA

Evaluations

R-work
0.179
R-free
0.222
Clashscore
3.7

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Kelch-like ECH-associated protein 1290
  • ConstructUNP residues 321-609
  • MutationsE540A E542A

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations