Deposited model

PDB 3D14|dpdb_xxb5lvba

Deposited model

Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)-ethyl]- thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea

Program
REFMAC 5.2.0005
Model type
Deposited
Purpose
Reference
Authors
Elling, R.A., Baskaran, S., Allen, D.A., Oslob, J.D., Romanowski, M.J.
Atoms
2,413
Residues
262
Protein chains
1
Unmodeled fraction
3.68%

Evaluations

R-work
0.210
R-free
0.257
Clashscore
7.3

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
serine/threonine kinase 6272
  • ConstructAurora A kinase domain, UNP residues 116-382
  • MutationsN186G K240R M302L

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations