Deposited model

PDB 6XIH|dpdb_y0chbzcl

Deposited model

Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp3 character and an exquisite selectivity profile

Program
REFMAC 5.8.0257
Model type
Deposited
Purpose
Reference
Authors
Dougan, D.R.
Atoms
4,101
Residues
504
Protein chains
2
Unmodeled fraction
14.58%

Evaluations

R-work
0.221
R-free
0.292
Clashscore
5.6

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Mitogen-activated protein kinase kinase kinase 5295—

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations