qFit model

PDB 5TQ8|dpdb_y2dv553t

qFit model

Design and Synthesis of a pan-JAK Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin

Program
Phenix 2.0_5824
Model type
Multiconformer
Purpose
Model Building
Atoms
5,511
Residues
291
Protein chains
1
Alternate-location fraction
88.66%
Ligand
7GS

Evaluations

R-work
0.160
R-free
0.207
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase JAK2298
  • ConstructUNP residues 837-1132
  • MutationsM1073S F1076T

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations