Deposited model

PDB 3QTF|dpdb_yzrb8ith

Deposited model

Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity

Program
PHENIX (phenix.refine)
Model type
Deposited
Purpose
Reference
Authors
Zapf, C.W., Bloom, J.D., McBean, J.L., Dushin, R.G., Nittoli, T., Ingalls, C., Sutherland, A.G., Sonye, J.P., Eid, C.N., Golas, J., Liu, H., Boschelli, F., Hu, Y., Vogan, E.M., Levin, J.I.
Atoms
1,985
Residues
207
Protein chains
1
Unmodeled fraction
8.41%

Evaluations

R-work
0.187
R-free
0.204
Clashscore
3.9

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Heat shock protein HSP 90-alpha226
  • ConstructN-terminal domain (UNP RESIDUES 10-236)

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations