Deposited model
PDB 2UWD|dpdb_z9z3vyjw
Deposited model
Inhibition of the HSP90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole, isoxazole amide analogs
- Program
- REFMAC 5.2.0019
- Model type
- Deposited
- Purpose
- Reference
- Authors
- Sharp, S.Y., Prodromou, C., Boxall, K., Powers, M.V., Holmes, J.L., Box, G., Matthews, T.P., Cheung, K.M., Kalusa, A., James, K., Hayes, A., Hardcastle, A., Dymock, B., Brough, P.A., Barril, X., Cansfield, J.E., Wright, L.M., Surgenor, A., Foloppe, N., Aherne, W., Pearl, L., Jones, K., McDonald, E., Raynaud, F., Eccles, S., Drysdale, M., Workman, P.
- Atoms
- 1,973
- Residues
- 209
- Protein chains
- 1
- Unmodeled fraction
- 11.44%
- Ligand
- MG
Evaluations
R-work
0.201
R-free
0.259
Clashscore
3.9
Macromolecules
The same in every model of this entry.
Data
L0 Raw
L1 Processed
L2 Models
L3 Evaluations