Deposited model

PDB 5EGM|dpdb_zw7f077d

Deposited model

Development of a novel tricyclic class of potent and selective FIXa inhibitors

Program
BUSTER 2.11.5
Model type
Deposited
Purpose
Reference
Authors
Meng, D., Andre, P., Bateman, T.J., Berger, R., Chen, Y., Desai, K., Dewnani, S., Ellsworth, K., Feng, D., Geissler, W.M., Guo, L., Hruza, A., Jian, T., Li, H., Parker, D.L., Reichert, P., Sherer, E.C., Smith, C.J., Sonatore, L.M., Tschirret-Guth, R., Wu, J., Xu, J., Zhang, T., Campeau, L., Orr, R., Poirier, M., McCabe-Dunn, j., Araki, K., Nishimura, T., Sakurada, I., Hirabayashi, T., Wood, H.B.
Atoms
2,565
Residues
289
Protein chains
2
Unmodeled fraction
2.69%
Ligand
NA

Evaluations

R-work
0.148
R-free
0.171
Clashscore
1.1

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Coagulation factor IX235
  • MutationA150R
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Coagulation factor IX62
  • ConstructUNP residues 131-191

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations