Deposited model

PDB 5WAL|dpdb_37ocqj7x

Deposited model

Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model

Program
BUSTER 2.11.6
Model type
Deposited
Purpose
Reference
Authors
Ultsch, M.H., Magnuson, S.
Atoms
2,498
Residues
286
Protein chains
1
Unmodeled fraction
5.3%

Evaluations

R-work
0.182
R-free
0.243
Clashscore
3.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Non-receptor tyrosine-protein kinase TYK2302
  • MutationsC936A Q969A E971A K972A S1016A C1142A D1023N

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations