Deposited model

PDB 4DTG|dpdb_4qxzlcrz

Deposited model

Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model

Program
REFMAC 5.6.0119
Model type
Deposited
Purpose
Reference
Authors
Svensson, L.A., Breinholt, J., Krogh, B.O., Hilden, I.
Atoms
4,431
Residues
500
Protein chains
3
Unmodeled fraction
1.38%

Evaluations

R-work
0.196
R-free
0.236
Clashscore
11.5

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Humanized recombinant FAB fragment, FAB 2021, of a murine antibody, light chain219——
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Humanized recombinant FAB fragment, FAB 2021, of a murine antibody, heavy chain222——
Entity 3
MoleculeChainsLengthOrganismUniProtDetails
Tissue factor pathway inhibitor66
  • ConstructKunitz-type protease inhibitor domain 2 (UNP residues 119-178)

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations