Dynamic PDB
Log in

Deposited model

PDB 6XVB|dpdb_5g4iy6mg

Deposited model

Crystal structure of the kinase domain of human c-KIT with a cyclic imidate inhibitor covalently bound to Cys788

Program
BUSTER 2.11.7
Model type
Deposited
Purpose
Reference
Authors
Schimpl, M., McAuley, K., Hoyt, E.A., Thomas, M., Bodnarchuk, M.S., Lewis, H.J., Barratt, D., Deery, M.J., Ogg, D.J., Bernardes, G.J.L., Ward, R.A., Kettle, J.G., Waring, M.J.
Atoms
4,803
Residues
585
Protein chains
2
Unmodeled fraction
10.82%
Ligand
O2H

Evaluations

R-work
0.192
R-free
0.223
Clashscore
1.2

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Mast/stem cell growth factor receptor Kit,Mast/stem cell growth factor receptor Kit328
  • Constructprotein kinase domain (551-934 del[688-755]),protein kinase domain (551-934 del[688-755])
  • MutationsI563S V569S Y609Q L631S M651E I662H D768H R804N V825D C844S L890S H894Y L912D L923D

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations