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Rerefined model

PDB 6FEX|dpdb_8wn1751q

Rerefined model

DDR1, 2-[4-bromo-2-oxo-1'-(1H-pyrazolo[4,3-b]pyridine-5-carbonyl)spiro[indole-3,4'-piperidine]-1-yl]-N-(2,2,2-trifluoroethyl)acetamide, 1.291A, P212121, Rfree=17.4%

Program
PHENIX 2.0_5824
Model type
Multiconformer
Purpose
Refinement
Atoms
2,880
Residues
289
Protein chains
1
Alternate-location fraction
3.11%
Ligands
CL, D6Z, IOD, MES

Evaluations

R-work
0.168
R-free
0.198
Clashscore
5.1

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Epithelial discoidin domain-containing receptor 1321
  • Constructtyrosine kinase domain, residues 593-913
  • MutationsDEL(730-735) 2-[4-bromo-2-oxo-1'-(1H-pyrazolo[4,3-b]pyridine-5-carbonyl)spiro[indole-3,4'-piperidine]-1-yl]-N-(2,2,2-trifluoroethyl)acetamide

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations