Dynamic PDB
Log in

Rerefined model

PDB 3RKZ|dpdb_ek52miyq

Rerefined model

Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor capable of significantly decreasing tumor volume in a mouse xenograft model.

Program
PHENIX 2.0_5824
Model type
Multiconformer
Purpose
Refinement
Atoms
2,095
Residues
208
Protein chains
1
Alternate-location fraction
1.44%
Ligand
06T

Evaluations

R-work
0.160
R-free
0.188
Clashscore
4.1

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Heat shock protein HSP 90-alpha226
  • ConstructN-terminal domain, UNP RESIDUES 10-236
  • MutationsDelta 16

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations