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qFit model

PDB 3RKZ|dpdb_ek52miyq

qFit model

Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor capable of significantly decreasing tumor volume in a mouse xenograft model.

Program
Phenix 2.0_5824
Model type
Multiconformer
Purpose
Model Building
Atoms
2,481
Residues
208
Protein chains
1
Alternate-location fraction
24.52%
Ligand
06T

Evaluations

R-work
0.153
R-free
0.181
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Heat shock protein HSP 90-alpha226
  • ConstructN-terminal domain, UNP RESIDUES 10-236
  • MutationsDelta 16

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations