Deposited model

PDB 5WEV|dpdb_g64qbvkz

Deposited model

Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model

Program
REFMAC 5.8.0155
Model type
Deposited
Purpose
Reference
Authors
Ultsch, M.H., Magnuson, S.
Atoms
2,624
Residues
295
Protein chains
1
Unmodeled fraction
7.52%

Evaluations

R-work
0.166
R-free
0.194
Clashscore
3.0

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase JAK2319
  • ConstructUNP residues 833-1132

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations