Deposited model

PDB 7B4N|dpdb_jm6e0w4y

Deposited model

Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human wild-type p53DBD bound to DNA and MQ: wt-DNA-MQ (II)

Program
PHENIX 1.18.2-3874
Model type
Deposited
Purpose
Reference
Authors
Rozenberg, H., Diskin-Posner, Y., Degtjarik, O., Shakked, Z.
Atoms
2,300
Residues
204
Protein chains
2
Unmodeled fraction
3.77%
Ligands
QN8, QNN, ZN

Evaluations

R-work
0.140
R-free
0.166
Clashscore
2.4

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Cellular tumor antigen p53200
  • Constructp53 human DNA binding domain
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
DNA target12—
  • Constructp53 DNA target
  • Mutations'

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations