Rerefined model

PDB 7B4F|dpdb_kptzqrla

Rerefined model

Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R282W mutant bound to DNA: R282W-MQ (I)

Program
PHENIX 2.0_5824
Model type
Multiconformer
Purpose
Refinement
Atoms
2,260
Residues
207
Protein chains
2
Alternate-location fraction
7.73%
Ligands
FMT, ZN

Evaluations

R-work
0.165
R-free
0.215
Clashscore
2.5

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Cellular tumor antigen p53200
  • Constructp53 human DNA binding domain
  • MutationR282W
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
DNA target12—
  • Constructp53 DNA target
  • Mutations'

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations