qFit model

PDB 7B4F|dpdb_kptzqrla

qFit model

Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R282W mutant bound to DNA: R282W-MQ (I)

Program
Phenix 2.0_5824
Model type
Multiconformer
Purpose
Model Building
Atoms
3,581
Residues
207
Protein chains
2
Alternate-location fraction
76.33%
Ligands
FMT, ZN

Evaluations

R-work
0.152
R-free
0.204
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Cellular tumor antigen p53200
  • Constructp53 human DNA binding domain
  • MutationR282W
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
DNA target12—
  • Constructp53 DNA target
  • Mutations'

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations