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Deposited model

PDB 2FVJ|dpdb_l6o5hp3q

Deposited model

A novel anti-adipogenic partial agonist of peroxisome proliferator-activated receptor-gamma (PPARG) recruits pparg-coactivator-1 alpha (PGC1A) but potentiates insulin signaling in vitro

Program
REFMAC 5.2.0005
Model type
Deposited
Purpose
Reference
Authors
Benz, J., Burgermeister, E., Flament, A., Schnoebelen, A., Stihle, M., Gsell, B., Rufer, A., Ruf, A., Kuhn, B., Maerki, H.P., Mizrahi, J., Sebokova, E., Niesor, E., Meyer, M.
Atoms
2,448
Residues
268
Protein chains
2
Unmodeled fraction
5.63%

Evaluations

R-work
0.189
R-free
0.246
Clashscore
8.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Peroxisome proliferator-activated receptor gamma271
  • ConstructLIGAND BINDING DOMAIN, RESIDUES 207-477
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Nuclear receptor coactivator 113
  • ConstructCOACTIVATOR FRAGMENT SRC-1, 13-mer peptide from Nuclear receptor coactivator 1

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations