Dynamic PDB
Log in

Rerefined model

PDB 4ZYC|dpdb_nrh6z1mx

Rerefined model

Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-MDM2 interaction with a distinct binding mode: Hdm2 (MDM2) complexed with cpd5

Program
PHENIX 2.0_5824
Model type
Multiconformer
Purpose
Refinement
Atoms
2,415
Residues
255
Protein chains
3
Alternate-location fraction
0%
Ligands
4SS, SO4

Evaluations

R-work
0.179
R-free
0.229
Clashscore
2.9

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
E3 ubiquitin-protein ligase Mdm296
  • ConstructN-TERMINAL DOMAIN, P53-BINDING DOMAIN, UNP residues 17-111
  • MutationL33E

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations