Deposited model

PDB 4CLJ|dpdb_vbxpi4vg

Deposited model

Structure of L1196M Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).

Program
CNX 2005
Model type
Deposited
Purpose
Reference
Authors
McTigue, M.A., Deng, Y.L., Liu, W., Brooun, A., Stewart, A.E.
Atoms
2,693
Residues
296
Protein chains
1
Unmodeled fraction
9.48%

Evaluations

R-work
0.196
R-free
0.229
Clashscore
9.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
ALK TYROSINE KINASE RECEPTOR327
  • ConstructTYROSINE KINASE DOMAIN, RESIDUES 1093-1411

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations